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帥酷隨意鐵蟲 (初入文壇)
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做了關(guān)于ICC生存分析的一篇文章 給了意見1) They need to detail more about the clinical, biochemical, tumor size, number of nodules, advanced or early, with or without vascular invasion, preoperative CEA and CA19-9 levels. In the literature was shown an interesting nomograms: the Wang nomogram was published in 2013 on a derivation cohort of 367 ICC patients resected at a single Asian center and the Hyder nomogram was published in 2014 from a multi-institutional cohort of 514 patients from 13 Western and Eastern centers. These nomograms are useful to validated prognosis and survival and could help the present study to confirm the results in a smaller population.2) Why they divided patients <58 or> 58 years?. BMI of these patients is important as the presence of Diabetes? Regarding others etiologies as hepatitis C, what is the frequency in these ICC cases? Did CEA , alpha feto protein and Ca19-9 levels were correlated with histologic expression? 第一個問題是讓附錄數(shù)據(jù) 還是讓做成這兩種列線圖呢（已經(jīng)做了生存曲線 感覺沒有做這個圖必要） 第二個問題 該如何回答呢 年齡分組是根據(jù)中位數(shù)取得，剩下的不知如何回答才好 |
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